(25) And lose himself, or be cast away.--Better, destroy himself, or suffer loss. The first word expresses a more direct act, as of self-destruction, and the second (see Note on Matthew 16:16) implies the thought of the forfeiture of something precious rather than of being absolutely rejected. It presents, so to speak, a slightly softened aspect of the previous words.

Verse 25. - For what is a man advantaged, if he gain the whole world, and lose himself, or be cast away? Godet's comment here is pithy and quaint: "Jesus supposes, in this twenty-fifth verse, the act of saving one's own life accomplished with the most complete success... amounting to a gain of the whole world. But in this very moment, the master of this magnificent domain finds himself condemned to perish! What gain to draw in a lottery a gallery of pictures... and at the same time to become blind!" "O flesh," writes Luther (quoted by Dr. Morrison), "how mighty art thou, that thou canst still throw darkness over those things, even to the minds of the holy!"

9:18-27 It is an unspeakable comfort that our Lord Jesus is God's Anointed; this signifies that he was both appointed to be the Messiah, and qualified for it. Jesus discourses concerning his own sufferings and death. And so far must his disciples be from thinking how to prevent his sufferings, that they must prepare for their own. We often meet with crosses in the way of duty; and though we must not pull them upon our own heads, yet, when they are laid for us, we must take them up, and carry them after Christ. It is well or ill with us, according as it is well or ill with our souls. The body cannot be happy, if the soul be miserable in the other world; but the soul may be happy, though the body is greatly afflicted and oppressed in this world. We must never be ashamed of Christ and his gospel.For what is a man advantaged if he gain the whole world,.... Or what profit will it be unto him? all the honours, riches, and enjoyments of it will be of no use and service to him if he himself is lost:

and lose himself; or his own soul; for he that loses his soul, which is his better and immortal part, loses himself:

or be cast away: finally, and eternally, or "suffer loss" of eternal happiness and glory; that is, perishes, and is destroyed with an everlasting destruction; See Gill on Matthew 16:26.